SCIENCE

Science & PEDs at Enhanced Games - What Performance Drugs Actually Do

21โ€“24 MAY 2026 ยทLAS VEGAS ยท8 MIN READ

What Are PEDs and How Do They Work

Performance Enhancing Drugs (PEDs) are a broad category of substances with different mechanisms of action. Not all PEDs are equal: they vary in effectiveness, health risk and discipline-specificity.

Enhanced Games officially sanctions PED use under medical supervision. This means athletes must:

  • Disclose substances used before competing
  • Pass cardiac and hepatological examinations
  • Have blood parameters monitored during competition

The prohibited substances list covers only those with proven direct life-threatening risk: cardiac stimulants, peptide toxins, hard narcotics.

EPO - Oxygen Delivery

Erythropoietin (EPO) is a hormone that stimulates red blood cell production, increasing oxygen transport to muscles. It is the most important PED for endurance athletes and swimmers.

Documented performance gain: 3โ€“7% in aerobic sports with 4โ€“12 weeks of use. For a 100m freestyle swimmer this would mean an improvement of roughly 1โ€“2 seconds - which would completely erase current world records.

EPO risks: blood thickening, risk of thrombosis and stroke (particularly at night when heart rate slows). Hence the requirement to monitor hematocrit levels.

HGH - Growth Hormone

Human growth hormone (HGH) accelerates muscle recovery, increases lean mass and improves movement economy. It works slower than steroids (effects visible after 3โ€“6 months) but is harder to detect with standard tests.

Performance gain: studies document 3โ€“5% strength improvement and 1โ€“3% aerobic performance improvement. In sprinting this may translate to 0.05โ€“0.15s better result over 100m.

HGH is particularly popular among sprinters and strongmen due to minimal risk at moderate doses.

Testosterone and Anabolic Steroids

Testosterone is the primary anabolic androgen - it increases muscle protein synthesis, strength and training aggression. At supraphysiological doses, effects on strength are dramatic.

Muscle mass gain: 5โ€“20 kg in a 12-week cycle (depending on dose and individual response). For weightlifters and strongmen this directly improves results by 10โ€“30%.

In sprinting, the direct effect is smaller (sprinting is more about neuromuscular speed than raw strength), but increasing fast-twitch muscle mass can bring 1โ€“3% improvement.

Risks: prostate enlargement, lipid disorders, fertility impact. Under medical supervision, long-term risk is moderate.

What Science Says About Record Potential

Sports physiologists from the University of Exeter and Johns Hopkins modeled performance results under full pharmacological conditions:

DisciplineCurrent RecordEG Projection
100m (M)9.58s (Bolt)9.35โ€“9.50s
50m freestyle (M)20.91s19.8โ€“20.3s
Weightlifting 102 kg+501 kg540โ€“580 kg

The findings are controversial: some scientists consider the projections overly optimistic, pointing out that human physiology has hard limits regardless of pharmacology.

Medical Safety

Enhanced Games has employed a panel of 12 sports physicians and physiologists. Each athlete undergoes before competing:

  • Cardiac echocardiography
  • Lipid and hepatological panel
  • Blood count with hematocrit
  • Neurological examination

Doctors have the right to medically disqualify an athlete even without their consent. This is a significant difference from classical doping, where there is no oversight.

Critics point out however that pre-competition tests do not eliminate long-term risks - the effects of years of supraphysiological hormone doses are poorly studied.